research intelligence workspace
Your hypothesis.
The evidence.
One workspace.
Not a reference manager. Not an AI chat.
Seren structures your research question, maps the literature against your hypothesis, and keeps a permanent record of every decision — and the evidence behind it.
Free for individual researchers · No credit card required
seren_
Here is how I would frame that:
Research question
"Does AAV6 produce more durable HSC engraftment than lentiviral delivery under matched transduction conditions?"
Preliminary signal: 12 papers found
7 support AAV6 advantage · 1 gap
the workspace
Everything a researcher needs.
From hypothesis to final draft.
One workspace. Every stage of the research lifecycle. Nothing separate, nothing disconnected.
● HSC AAV6 vs lentiviral · root
9 papers · evidence amber
● CD34+ tropism limits dose
6 papers · evidence green
○ Ex vivo → in vivo translation
2 papers · evidence grey
seren_ > gap = BM-HSC matched conditions
Nature Methods · directly addresses
Blood · matched transduction protocol
Cell · contradicts dose assumption
Theory Mapper
Map frameworks across all papers
Method Auditor
Compare methodology + blind spots
Evolution Timeline
How the field's thinking changed
Quote Miner
10 most citable sentences
Weakness Scanner
5 weakest arguments in the field
Bridge Builder
Adjacent fields your field ignores
Replication Audit
What has and hasn't replicated
Future Agenda
What the field needs to ask next
Jargon Translator
Plain English from all your papers
seren_ > linking [Naldini 2022] to capsid pathway
you_ > /find papers on CD34 engraftment post-myeloablation
→ 8 papers found · 3 relevant · added to review queue
you_ > /add mechanism capsid tropism limits CD34 dose
→ mechanism logged · linked to root hypothesis
you_ > /decision proceed AAV6 phase-1 ex vivo
→ decision recorded · confidence: high · Mar 8
seren_ > Aim 1 references 6 papers from your foundation
flow_cyto_run3.csv
2.1 MB · 847 events · 3 populations · QC flag on col 7
engraftment_week6.xlsx
n=24 · primary endpoint · 3 arms
seren_ > The QC flag in run3 affects 12% of events — do you want to exclude col 7 before running the engraftment comparison?
KNOWN
● AAV6 efficiency above 800bp payload
CONTESTED
⚡ Dose translation ex vivo → in vivo
Naldini 2021 vs Aiuti 2022
UNKNOWN
○ BM-HSC matched conditions · no pub data
§2.1 — unsupported claim
"...well-established safety profile..." — no citation. Naldini 2021 should support this.
§3.2 — contradicts decision log
Claims BM-HSC data exists. Your uncertainty map flags this as unknown.
Scanning PubMed every 6h against your hypothesis
Mimitou et al., 2025 — new
Addresses your BM-HSC gap directly · review
Schiroli et al., 2025 — new
Contradicts Naldini 2021 on dose curve · review
1 paper in your foundation retracted — flag
Mar 8 · High confidence
Proceed with AAV6 ex vivo protocol
Based on: Dever 2016 · Romero 2019
Uncertainty accepted: no BM-HSC data
Feb 22 · Medium confidence
Exclude mobilised HSCs from Phase 1 arm
Based on: Aiuti 2022 · Naldini 2021
what makes seren different
Zotero / Mendeley
Stores your papers. Organises your library. Tells you nothing about what the collection means for your question.
→Seren connects every paper to your hypothesis. You see what supports it, what contradicts it, and what the literature has not answered yet.
Elicit / Consensus
Summarises papers. Finds relevant results. Produces outputs with no memory of your specific question or what you decided.
→Seren tracks what you decided based on the evidence — and builds a permanent record of why, so you can always prove you thought carefully.
ChatGPT / Claude
Answers questions. Starts fresh every session. Has no knowledge of your specific study, your hypothesis tree, or your prior decisions.
→Seren is a persistent workspace. It remembers every hypothesis, every evidence card, every uncertainty you accepted — and searches the literature in that context.
A research question structured.
Evidence mapped against a hypothesis.
Decisions logged with the reasoning behind them.
A workspace that remembers what you built.
“
Finally a tool that treats my research question as the starting point, not an afterthought.
— Postdoctoral researcher, biomedical sciences
Start with
your research question.
Free for individual researchers.
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